Soft Tissue Regeneration of Infected Wounds Following the Use of Microcurrent as the Sole Therapeutic Modality

S.M. Kaye, D. Stubbs
American Institute of Regeneration, Pacific Palisades, CA

It has long been recognized that in addition to the massive and complex biochemical and cellular response that occurs as a result of significant injury, tissue repair and regeneration is dependent on highly specific changes in electrical fields at the site of damage. These changes generate what has been called a micro current of injury and effect the up-regulating of an array of growth factors and cytokines within the intracellular matrix. It also acts as an electro-attractant that influences the direction of migration of regenerating peripheral neurons, fibroblasts, and the cellular component of the immune system.

The microcurrent device that we are utilizing produces a very specific waveform of ultra-low direct electrical current (in the nano-ampere range) and frequency (0.0007 Hz). We believe that this unique current results in the electrons passing into the Electron Transport Chain (ETC) and maximizing the production of Adenosine Triphosphate (ATP) by the mitochondria. The electrons are in free form, so they also have a powerful intracellular antioxidant effect.

We wish to present a series of clinically severe, intractable, and generally infected wound cases that clearly demonstrate the dramatic efficacy of introducing specific microcurrents as a sole therapeutic modality in comparison to the use of all standard wound-care techniques. Of equally great significance, it has been demonstrated that the precise quantitative rate of tissue regeneration in wounds receiving these currents exclusively does not change with the age of the patient, contrary to most other published studies. This holds true for individuals ranging in age from 20 to 80 years.

We have included an example application of microcurrent in this case study: Mrs. MS, a 74 year-old woman, was an inpatient in the hospital awaiting a below-knee amputation. Two weeks earlier, she had undergone a left hemi-forefoot amputation to remove a gangrenous 2nd toe. Her other problems included; peripheral vascular disease, peripheral neuropathy, previously undiagnosed Type-2 Diabetes, and hypertension. She was treated with a 1 milliampere current for 23 minutes followed by a 400 nano-ampere current for two hours on a daily basis. After nine months of treatment, she was living at home, mobile on both her legs; her diabetes was under control (HA1c in the non diabetic range < 6.0) on no medication; her hypertension was under control on no medication; she had palpable pulses in both feet; she had sensation returning to her left foot; and her wound was in the process of healing. At 12 months, the wound on her foot had fully healed without scar tissue and, where a large volume of her foot was missing, her tissue had regenerated.

This case demonstrates the body's ability not only to heal but also regenerate when a proper environment is provided to the cells. Mrs. MS was treated in a generic setting designed only to work on the body’s cells as an intracellular antioxidant and stimulate ATP production via the mitochondrial Electron Transport Chain. The result of providing this cellular environment was that this patient was able to achieve a much higher level of healing of her skin, subcutaneous tissues, circulatory system, nervous system, and her endocrine system.

Keywords: Tissue regeneration, Microcurrent, ATP