Methuselah Foundation – Extending Healthy Human Life
LONG TERM STRATEGY
Organ Printing: It’s Not Science Fiction Anymore
“In the future we’ll be able to harness nature’s ability to form organs and build our own.”
Dr. Gabor Forgacs made that prediction. Now, he is making it a reality. Gabor is a University of Missouri researcher doing groundbreaking work in regenerative medicine. He is also the Scientific Founder and Chief Scientific Officer of Organovo, the latest company to receive support from you, the donors of the Methuselah Foundation. As we work to identify breakthrough technology that will help us reach our shared goal of extending healthy human life, Organovo stands out. Thanks to your contributions we are able to assist them as they apply their proprietary technology to “print” new organs.
Read more about Gabor and Organovo and watch a video that explains the technology behind his remarkable achievements
NEAR TERM STRATEGY
New Site Feature: Tips4Life
Many of you have asked: what can we do now to extend life? Through My Bridge 4 Life™, Methuselah Foundation fills that immediate need. My Bridge 4 Life is an online and offline community tool that takes the overwhelming nature of a major health crisis; divides it into manageable phases; sets goals for each phase with each user and their community; AND builds a wellness plan for life in the process.
In an early development stage, the first application Tips 4 Life is a global database of real-world wisdom. Take a few minutes today to post your experiences and insights and ask friends and family to share their tips related to a life-threatening health challenge they have faced.
Learn about My Bridge 4 Life at Mfoundation.org
MID TERM STRATEGY
Harvard Scientist Explores: Longevity, Red Wine & Calorie Restriction
Fifteen years ago David Sinclair moved half way around the world to pursue his interest in longevity. David didn’t want to take the usual route, looking for the genes that ended life, he wanted to figure out how to extend it.
Today he strives to devise ways to prevent and treat major diseases by manipulating genes that control how fast we age. David has been a frontrunner in the dramatic shift in research related to the aging process. Ignoring the conventional wisdom that the aging process was too complex to find drugs that could slow it, he works to uncover single genes that could dramatically extend the lifespan of laboratory organisms such as yeast, worms, flies and mice.
This transformation has left us with the fact that the rate of aging is not predetermined – it is naturally regulated by a few critical genes. These genes underlie the remarkable effects of the diet known as calorie restriction (CR), which delays aging in nearly every species tested, from yeast to primates. According to Dr. Sinclair, CR is currently the only treatment that is proven to prevent all diseases of aging including cancer, heart disease, osteoporosis, diabetes and neurodegeneration.
In his own words: “Recent studies in our lab and others…
MFoundation News Coverage
KTLA in Los Angeles did a story on The Methuselah Foundation, interviewing our Chief Marketing Officer Roger Holzberg and covering the 3-part strategy and Organovo (read more on Organovo in this newsletter). Take a look.
A recent press release covered the 3-part strategy and another about our support of Organovo was released out this week. All press releases are now posted on the site.
“How many lives will the Methuselah Foundation save? How about at least 66 million? Here’s how I estimate that. Current world population of 6.6B. Conservatively assume 1% die each year from aging related causes, so that’s 66 million aging driven deaths per year. Accelerate the date by which aging ceases to be a routine cause of death by just a single year, and 66 million lives will have been saved. We think such a one year acceleration is a modest goal for the Foundation. If it stimulates a 10 year acceleration, that would mean 660 million lives saved! We want to help the Foundation do that, and to be there to enjoy the results.”
The Shapard Family
Thomas Shapard, Joanne Shapard, and Catherine Phillips
Foundation Profile: David Sinclair
David A. Sinclair, Ph.D. is the Co-Director of the Paul F. Glenn Laboratories for the Molecular Biology of Aging, an Associate Professor of Pathology at Harvard Medical School, Associate Member of the Broad Institute for Systems Biology, co-founder of Sirtris Pharma-ceuticals and a competitor for the MPrize. A native of St. Ives Australia, in 1995 he joined Leonard P. Guarente (another MPrize competitor) at MIT to pursue his interest in longevity and aging. He has been at Harvard since 1999.
Join The 300
Last call! This special group of donors has responded to the challenge to contribute $1000 a year for 25 years. Fill one of the few remaining slots and your donation will go to work immediately funding innovative technology that will change science forever. As a 300 member you’ll get advance notice of news and events, have the opportunity to participate in exclusive webinars, receive a monthly email from Dave Gobel and have the satisfaction of knowing your gift will result in extended healthy life for yourself, your family and all humanity.
More news on The 300 monument coming soon – join now and have your name and message included.