LOWERING OF METABOLISM - A POSSIBLE METHOD OF HUMAN LIFE SPAN PROLONGATION





V.E. Chernilevsky

Moscow state university of medicine and dentistry, Delegatskaja str., 20, Moscow, 103473, Russia



Purpose: The possibilities of lowering basal metabolism (LBM) in man with aim of longevity have been investigated. The method is based on the data that at many mammalia in state of hypobiosis BM is lowered very much and aging is delyed independently from the mechanisms, and after hypobiosis the process of self-renovation of tissues is activated, In addition the life span of some species (Microtus, Soricidae etc,) is able to increase in several times. Results: In the experiments on life prolongation of mice, don't flowing into hypobiosis, us have been success LBM by hypoxi-hypercapnic gaseous medium. It is known that in man during sleep the respiration and puls rate, body temperature, oxygen consumption (VO2) and carbon dioxide discharge (VCO2) are decreased On the background fool muscular relaxing and starvation (BFMRS) it causes LBM for 20%, The further LBM during sleep is possible for training of respiration on the BFMRS. Such trainings are known in active state. The first economy of respiration is reached by limitation depth of breath and expiration. Then the decrease of respiration rate has been working by training in breath holding and stepped respiration on the BFMRS. For the time the slow respiration has been automating. It is established that in such respiration VO2 and VCO2 are lowering twice, oxygen utilisation coefficient is increasing stability to hypoxia and resistance of organism to different diseases are working, viability is raising. BFMRS relives the respiratory training, makes them more effective and allows LBM twise. Conclusion: Application of automatic rhythm 2 respiration a min on the BFMRS for 7-8 hr sleep essentially should LBM and delay aging. It is known that during sleep the secretion of anabolic hormones is raised that causes to activity of synthesis of proteins and nucleic acids, to self-renovation of cells and tissues. After sleep these processes should be intensified by special training widening of reserve possibilities of organism.



Key words: Lowered metabolism, Longevity







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