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Abstracts invited or accepted so far
This list includes invited abstracts, those accepted for oral presentation and those accepted for poster presentation.
Formation and damaging effects of superoxide in mitochondria: relevance to mitochondrial aging
I.B. Afanas'ev
Adrenal cortex macrophages during ageing and after dexamethasone administration
H. Almeida, J. Ferreira and D. Neves
Delaying the Mitochondrial Decay of Aging
Bruce N. Ames
Absolute Versus Relative Caloric Intake: Clues To The Mechanism Of Calorie/Aging-rate Interactions
R.M. Anson
The biomedical relevance of microbial catabolic versatility
J. A. C. Archer
Alpha lipoic acid increases sodium potassium ATPase and reduces lipofuscin accumulation in discrete brain regions of aged rats
P. Arivazhagan, D. Ayusawa, C. Panneerselvam
Gene Networks, Individual Senescence, and Timeless Aging
R. Arking and C.N. Giroux
The Magnificent IL-7; an interleukin for rejuvenating the immune system
Richard Aspinall, Sian Henson, Jeffrey Pido-Lopez and Pa Tamba Ngom
Social, Political, and Ethical Obstacles to Human Life Extension
Steven N. Austad
The extent and significance of telomere loss with age
D.M. Baird and D. Kipling
Effect of Dehydroepiandrosterone and Related Steroids on Neurogenesis in Adult Rat Brain
Z. Bandpey and J. Herbert
Oxygen Radicals and Aging
G. Barja
Cellular Nutrient Sensing and Longevity
N. Barzilai, L. Rossetti, M. Brownlee, M. Hawkins, J. Crandall
Comparative estimation of adaptation biomarkers
Belozerova L.M.
Decay of mitochondrial metabolic competence in the aging cerebellum
C. Bertoni-Freddari, P. Fattoretti, B. Giorgetti, M. Solazzi, M. Balietti
Cytochrome oxidase activity in hippocampal synaptic mitochondria during aging: a quantitative cytochemical investigation
C. Bertoni-Freddari, P. Fattoretti, B. Giorgetti, M. Solazzi, M. Balietti
Demonstration of differences in the action of several metabotropic and ionotropic glutamate agonists on intracellular reactive oxygen species and the Na-pump
A. Boldyrev, E. Bulygina, D. Carpenter and W. Schoner
Alternative lengthening of telomeres: a telomerase independent route to cellular immortality
D. Broccoli
New limbs for old - lessons from the newt
Jeremy P. Brockes
Growth hormone alters components of the glutathione metabolic pathway in dwarf mice
H.M. Brown-Borg and S.G. Rakoczy
Testing the Free Radical Theory of Ageing in Bats
A.K. Brunet-Rossinni
Aging of cardiac myocytes and mitochondrial turnover
A. Terman, U.T. Brunk
Selective vulnerability in ageing rat sympathetic neurons
K.P. Gatzinsky, C. Thrasivoulou, M. Campioni-Noack, C. Underwood, T. Cowen
Consequences of cellular senescence and prospects for reversal
Judith Campisi
Mouse Models and Human Aging
Mario R. Capecchi
Mr. Yuck meets the Grim Reaper: why living longer is not such a bad thing
Arthur Caplan
Looking for immunological risk genotypes
C. Caruso, A. Aquino, G. Candore, L. Scola, G. Colonna-Romano, D. Lio
Vitamin E-deficiency and aging effect on expression levels of GAP-43 and MAP-2 in selected areas of the brain
T. Casoli, G. Di Stefano, A. Delfino, C. Bertoni-Freddari
Measurement of the 4834 bp mitochondrial DNA deletion level by Real Time PCR in aging rat liver subjected or not to caloric restriction diet
P. Cassano, A.M.S. Lezza, C. Leeuwenburgh, P. Cantatore, M.N. Gadaleta
A high-throughput screening system for human genes extending life-span
C. Chen and R. Contreras
Excitotoxic neurodegeneration induced by intranasal administration of kainic acid in C57Bl/6 mice
Zhiguo Chen, Hans-Gustaf Ljunggren, Nenad Bogdanovic, Inger Nennesmo, Bengt Winblad, Jie Zhu
Generally biological approach to a problem of aging
V.E. Chernilevsky
Lowering of metabolism - a possible method of human life span prolongation
V.E. Chernilevsky
Model of aging taking into account packing of cells
V.E. Chernilevsky, A.N. Zajarny
Recovery of mitogenic signaling by reduction of caveolin-1 in senescent cells
Kyung A Cho, Sung Jin Ryu, Kyung Tae Kim, Ik Soon Jang and Sang Chul Park
Human Supercentenarian Epidemiology and the Implications for Longevity
L. Stephen Coles
Gender differences in Alzheimer's disease neuropathology
E.H. Corder, E. Ghebremedhin, D.R. Thal, T.G. Ohm, H. Braak
Pathways to exceptional human longevity: New evidence from the 1982-1999 National Long Term Care Surveys
L.S. Corder
Use of zolpidem in over-75 year old patients with sleep disorders and comorbidities
A. Cotroneo, P. Gareri, S. Cabodi
Chronic treatment with a precursor of phosphatidylcholine ameliorates morphological and behavioural effects of ageing in the rat hippocampus
D. Crespo, M. Megias, C. Fernandez-Viadero, and R. Verduga
Non-invasive Human Oxidative Stress Profiling and its Biomedical Application
Richard G. Cutler
Decline in proteasome and lon protease activity with age: transcriptional dysregulation or inhibitor accumulation?
Kelvin J.A. Davies
Collective Suttee: If Not Everyone Can Afford Life-Extension, Does That Mean No One Should Have It?
J.K. Davis
Investigation of the signalling pathways involved in the proliferative life span barriers in Werner Syndrome fibroblasts
T. Davis, R.G.A. Faragher, C.J. Jones, D. Kipling
WILT: an ambitious but truly un-escapable anti-cancer therapy
A.D.N.J. de Grey, S.E. Artandi, F.C. Campbell, I. Dokal, L.J. Fairbairn, G.J. Graham, C.A.B. Jahoda, A.C.G. Porter
Biogerontologists' duty to discuss timescales publicly
A.D.N.J. de Grey
Remodeling of Age- and Diabetes-Related Changes in Extracellular Matrix
R.C. deGroof
Mitochondrial transcription factor A (TFAM) acetylation and age-related mtDNA and TFAM contents in several rat tissues
M.M. Dinardo, C. Musicco, V. Pesce, F. Fracasso, F. Milella, A.M.S. Lezza, G. Gadaleta, P. Cantatore, M.N. Gadaleta
Analysis of the Role of p53 in Aging Using Mouse Models
L.A. Donehower
Observation of Preventive and Therapeutic Effects of Antithrombin-Ⅲ on Experimental Disseminated Intravascular Coagulation
Hongjiang Dong, Shuhua Zhang, Lin Li
T cell replicative senescence: pleiotropic effects on human aging
R.B. Effros
Telomere-initiated cellular senescence is a DNA damage checkpoint-mediated response
F. d'Adda di Fagagna, P.M. Reaper, L. Clay-Farrace, T. von Zglinicki, G. Saretzki and S.P. Jackson
Camptothecin sensitivity in Werner's syndrome fibroblasts as assessed by the COMET technique
J. Lowe, A. Sheerin, K. Jennert-Burston, J. Bird, M.H.L. Green & R.G.A. Faragher
Chronic aluminum administration to old rats results in increased levels of brain metal ions and enlarged hippocampal mossy fibres
P. Fattoretti, C. Bertoni-Freddari, M. Balietti, B. Giorgetti, M. Solazzi, P. Zatta
Senescence Marker Protein-30 (SMP30) as a novel anti-ageing molecule
D. Feng, Y. Kondo, A. Ishigami, M. Kuramoto, T. Machida, N. Maruyama
Motor and cognitive recovery induced by bone marrow stem cells grafted to striatum and hippocampus of impaired aged rats: functional and therapeutical considerations
C.I. Fernandez, E. Alberti, Y. Mendoza, J. Collazo, L. Martinez, J.C. Rosillo
Environmental enrichment-behavior-oxidative stress interactions in the aged rat: issues for therapeutical approach in human aging
C.I. Fernandez, J. Collazo, Y. Bauza, O. Lopez
Evidence and identification of preferential protein targets for age-related modifications in peripheral blood lymphocytes
S. Poggioli, J. Mary, H. Bakala and B. Friguet
2003 Flow chart of biochemical and physiological interactions in human aging
J.D. Furber
In vivo demonstration of anti-senescence effect of natural hydrophilic antioxidant carnosine
S. Gallant and A. Boldyrev
Oxidative stress and TGF-beta1: triggers of premature senescence in adult human prostate fibroblasts?
R. Gander, G. Untergasser, H. Rumpold, E. Plas, L. Tadic, P. Berger
Early-Life Programming of Aging and Longevity: The Idea of High Initial Damage Load (the HIDL Hypothesis)
Leonid A. Gavrilov and Natalia S. Gavrilova
Reliability-Engineering Approach to the Problem of Biological Aging
Leonid A. Gavrilov and Natalia S. Gavrilova
Does Exceptional Human Longevity Come With High Cost of Infertility? Testing the Evolutionary Theories of Aging
Natalia S. Gavrilova, Leonid A. Gavrilov, Victoria G. Semyonova, Galina N. Evdokushkina
The Methuselah Mouse Prize
D. Gobel
Age-related muscle loss and progressive dysfunction in mechano sensitive growth factor signalling
G. Goldspink
Age related endocrine disfunctions in non-human primates
N.D. Goncharova, B.A. Lapin
Longevity and survival factors implicated in human ageing and longevity
E.S. Gonos
Carbon-based pharmaceuticals as a novel prolongevity strategy
E.N. Gorban, V.K. Koltover
Regular exercise: A possible anti-oxidative strategy in ageing
S. Goto, Z. Radak, H.Y. Chung, H. Naito, R. Takahashi, H. Nakamoto
Protective effects of mutant ubiquitin in transgenic mice
D.A. Gray, M. Tsirigotis, J. Brun, M. Tang, M. Zhang, M. Beyers, and J. Woulfe
The effect of environmental versus genetic influences on immunosenescence
B. Grubeck-Loebenstein
Rockfish: Long-Lived Animals with "Negligible Senescence"
John C. Guerin
Telomerase and Regenerative Medicine
Calvin B. Harley
What Do Hormones Have to Do with Aging? What Does Aging Have to Do with Hormones?
S.M. Harman
Immortal Ethics
John Harris
Regenerative Medicine: Systematic Application of Biotechnology, Bioengineering, Nanotechnology and Information Sciences for the Improvement of Human Health
William Haseltine
Regulation of telomerase activity throughout life: rescue effect or cancer
M.F. Haussmann, C.M. Vleck
Problems of health for fourth age in albania
Edmond Ymer Haveri, Altin Xhikneli
Modification of IL-7 and its use in the treatment of thymic involution
S.M. Henson, R. Aspinall
The Role of Nutrition in Human Health, Disease, and Aging - A Practical Approach
C.B. Heward
Naturally long-lived animal models for the study of slow aging and longevity
Donna J. Holmes
Which ages first--the chicken or the egg? A comparative test of the ovarian depletion hypothesis of female reproductive aging
Donna J. Holmes, Mary Ann Ottinger, Sharon L. Thomson, Julie M. Wu
Development of calorie restriction mimetics as a prolongevity strategy
D.K. Ingram
Epigenetic therapy
J.P. Issa
The role of viruses and of APOE in dementia
R.F. Itzhaki, C.B. Dobson, S. Shipley, M.A. Wozniak
Respiration, coupling and ROS in senescent human fibroblasts
Eveline Huetter, Kathrin Renner, Erich Gnaiger, Gerald Pfister and Pidder Jansen-Duerr
Aging, Exercise and Photochemicals: Promises and Pitfalls
Li Li Ji
Fruit polyphenols in brain aging: Effects on Signaling, Neurogenesis and Behavior
J.A. Joseph, G. Casadesus, D. Ingram and B. Shukitt-Hale
Mechanism of telomere shortening by oxidative stress
S. Kawanishi and S. Oikawa
Genetic and environmental determinants of aging and longevity: the lesson of the life-extending mutations
A.V. Khalyavkin, A.I. Yashin
Telomere shortening: is it really basic cause of senescence?
A.V. Khalyavkin
What is the age of the age-related mutations in mitochondrial DNA?
K. Khrapko
Effect of Physical Activity Levels on Bone Strength
K. Kikkawa
Iron Accumulation During Cellular Senescence
D.W. Killilea, S.L. Wong, H.S. Cahaya, H. Atamna, B.N. Ames
Genetic correction of mitochondrial respiratory chain deficiencies
M.P. King
Intestinal stem cell ageing: role of mitochondrial mutation?
T.B.L. Kirkwood
Zebrafish as a novel vertebrate model of functional aging and gradual senescence
Shuji Kishi and Junzo Uchiyama
Interventions in aging and age-associated pathologies by means of nutritional approaches
K. Kitani, T. Yokozawa, T. Osawa
On the pro-inflammatory phenotype of senescent cells: the p53-mediated ICAM-1 expression
D. Kletsas, H. Pratsinis, G. Mariatos, V.G. Gorgoulis
Directing the Repair of Damaged DNA and Genetic Mutations in vivo
E.B. Kmiec
Longevity, ionizing radiation, and hormesis: the reliability-theory point of view
V.K. Koltover
Apolipoprotein E genotype and the age at menopause
J. Koochmeshgi, S.M. Hosseini-Mazinani, S.M. Seifati, N. Hosein-Pur-Nobari, L. Teimoori-Toolabi
An appetite for death
J. Koochmeshgi
Reproductive switch and aging- the case of leptin change in dietary restriction
J. Koochmeshgi
Mechanisms for the Negative Effects of elevated Superoxide Dismutase Levels
A. Kowald
The molecular chaperones and the process of cellular immortalization in vitro
J. Kroll
Evidence for increased oxidative stress during replicative senescence of human peritoneal mesothelial cells in vitro
K. Ksiazek, A. Breborowicz, A. Joerres, J. Witowski
Replicative senescence of human peritoneal mesothelial cells in vitro - a new model for cytogerontological studies
K. Ksiazek, A. Breborowicz, J. Witowski
Relocalized redox-active lysosomal iron is an important mediator of oxidative stress-induced DNA damage
T. Kurz, A. Leake, T. von Zglinicki and U.T. Brunk
Cost of reproduction and susceptibility to heat stress in fruitflies
S. Ladonni, S.M. Hosseini-Mazinani, J. Koochmeshgi
Intervening on cardiovascular aging in health to beat cardiovascular disease
E.G. Lakatta
Cell signaling and apoptosis in aging
C. Leeuwenburgh
Medical Time Travel as a Bridge to Negligible Senescence
Jerry B. Lemler
Glutathione metabolism during aging and in diseases
Rui-Ming Liu
Association of MMPs, TIMPs and proteoglycans with aging and osteoarthritis in mouse temporomandibular joint
A. Gepstein, G. Arbel, E. Livne
Neutrophil superoxide generation and phagocytosis are reduced in elderly trauma patients: relation to increased infections rates and altered corticosteroid levels
S.K. Butcher, H. Chahal, V. Killampali, E.K. Alpar and J.M. Lord
The role of cellular senescence may be to prevent division of neighboring cells
M.D. Lynch
Transcriptomic study of H2O2-induced premature senescence of human diploid fibroblasts using a low-density cDNA array
J.P. de Magalhaes, V. Migeot, V. Mainfroid, F. de Longueville, J. Remacle, O. Toussaint
Aging and vitamin E deficiency are responsible of altered RNA pathways
M. Malatesta, C. Bertoni-Freddari, P. Fattoretti, B. Baldelli, S. Fakan, G. Gazzanelli
Cirrhosis progression as a model of accelerated senescence: affecting the biological aging clock by a breakthrough biophysical methodology
G. Marineo, F. Marotta, G. Sisti
The aging/precancerous gastric mucosa: a preliminary antioxidant interventional trial
F. Marotta, R. Barreto, H. Tajiri, H. Fuji, E. Fesce
SMP30 knockout (SMP30-KO) mouse as an ageing mode
N. Maruyama, A. Ishigami, M. Kuramoto, S. Handa, S. Kubo, Y. Kasahara
A Longitudinal Study of Skeletal Muscle Aging and The Impact of Dietary Restriction in Rhesus Monkeys
S. H. McKiernan, R. J. Colman and J. M. Aiken
Mitochondrion-mediated apoptosis is enhanced in long-lived alphaMUPA transgenic mice and calorically restricted wild-type mice
O, Tirosh, I. Zusman, S. Yahav, R. Miskin
Lack of correlation between mitochondrial ROS production and lifespan in Drosophila
S. Miwa, M.D. Brand
Immunomodulation, ageing and successful ageing: role of Metallothionein
Eugenio Mocchegiani, Robertina Giacconi, Mario Muzzioli, Catia Cipriano
Influence of Avercectin C on Growth of the Transformed Chinese Hamster Cells
S. Mohammadzadeh, A.V. Kolesnikov, L.Yu. Prokhorov
Research of the low doze gamma-irradiation influence on life span and aging speed of Drosophila melanogaster
A.A. Moskalev
Antibodies Against beta-Amyloid Slow Cognitive Decline in Patients with Alzheimer's disease
Roger M. Nitsch and Christoph Hock
Algae extract protection effect on oxidized proteins level in human keratinocytes
C. Nizard, S. Poggioli, C. Heusele, A.L. Bulteau, M. Moreau, A. Saunois, S. Schnebert, B. Friguet
Heat Shock Protein (HSP) 47 expression in aged, photo-aged and senescent normal human fibroblasts. Modulation by salix alba extract
E. Noblesse, C. Boisde, M. Moreau, A.M. Faussat, S. Schnebert, C. Nizard
How an individual fecundity pattern looks in Drosophila and Medflies
V.N. Novoseltsev, R. Arking, J.R. Carey, J.A. Novoseltseva, A.I. Yashin
Obesity, Infectious Diseases, and Forecasts of Human Life Expectancy + The Demographic Impact of Immortality
S.J. Olshansky, D. Ludwig, B.A. Carnes, J. Brody, L. Hayflick, R. Butler
The phenotypic expression of age-associated mtDNA deletion mutations in rat skeletal muscle is fiber type-dependent
Jeong W. Pak and Judd M. Aiken
Functional Efficiency of the Senescent Cells: Replace or Restore?
S.C. Park
Prevention of T cell ageing will rejuvenate anti-cancer efficacy
Graham Pawelec
Targeting Age-Related Modification and Dysfunction of Heart Cell Membranes: Engineering Reversal with Omega 3 Fatty Acids and Antioxidants
S. Pepe, S.J. Sollott, F.L. Rosenfeldt and E.G. Lakatta
Mechanism(s) responsible for exercise-induced cardioprotection
Scott K. Powers
Possibility increase life span of animals and man more than 1.5-2 times
L. Yu. Prokhorov
Age-related impairment of the transcriptional responses to oxidative stress in the mouse heart
M. Edwards, Sarkar D., Klopp R., Morrow J.D., Weindruch R., Prolla T.A.
An epidemiology study
M.A. Qajar Koohestani, B. Shabankhani
Molecular mechanisms of anti-ageing hormetic effects of repeated mild heat stress on human cells
S.I.S. Rattan
Selenium, glutatione peroxidase, glutathione and malondialdehyde levels in elderly subjects from the Belfast Elderly Longitudinal Free-living Aging Study (BELFAST)
I.M. Rea, D. McMaster, J. Donnelly, L.T. McGrath, I.S. Young
Molecular Mechanisms and Signaling Pathways in Muscle Atrophy in Immobilization and Aging
A.Z. Reznick and M. Bar-Shai
Regenerative medicine: Antagonic-Stress® therapy in stress and aging. I. Preclinical synthesis - 2003
D. Riga, S. Riga and F. Schneider
Prolongevity medicine: Antagonic-Stress® drug in stress, aging and related diseases. II. Clinical review - 2003
S. Riga, D. Riga and F. Schneider
Quest for Mitochondrial Markers of Impaired Post-Ischaemic Functional Recovery in the Ageing Heart and for Clinical Therapeutic Strategies
F.L. Rosenfeldt, S. Pepe, A. Hadj, F. Miller, P. Nagley
Prometheus' vulture and the promise of stem cells
N. Rosenthal, A. Musaro
Serum heat shock protein 70 and the 2437T allele of the heat shock protein 70-Hom gene in the BELFAST study
Owen A. Ross, Martin D. Curran, Karen A. Crum, Yvonne A. Barnett, Derek Middleton, I. Maeve Rea
Digital transcriptome analysis of the aging mouse cerebellum
A. Rotter, M.C. Popesco, K. A. Rejniak, J. A. Besco, A.M. Frostholm
Ultrasound in determining pleural effusion nature as an alternative way for aspiration specialy in old age people
Hamidreza Sajadieh, Reza Modares
Using Tissue Engineering to Produce an Unlimited Supply of Tissues and Organs
Michael V. Sefton
Age-associated accumulation of post-translational oxidative modifications on skeletal muscle phosphorylase B in fisher 344 rats
V.S. Sharov, C. Schoneich
Telomerizing Somatic Cells for Tissue Engineering
J.W. Shay and W.E. Wright
RAGE, a new pleiotropic antagonistic gene?
A. Simm, S. Daoud, J. Wagner, C. Casselmann, R.-E. Silber
Mitochondria as coordinators of aging and cancer
Keshav K. Singh
Alzheimer Disease: causes, consequences, and surprises
Mark A. Smith, Xiongwei Zhu, Gemma Casadesus, Gjumrach Aliev, Osamu Ogawa, Akihiko Nunomura, Atsushi Takeda, James A. Joseph, Robert B. Petersen, George Perry
Rapid identification of candidate CR mimetics using microarrays
S.R. Spindler, J.D. Dhahbi, P.L. Mote, H.J. Kim, and T. Tsuchiya
The promises and pitfalls of planning for demographic change
Gregory Stock
The effect of vitamin E on the protein homeostase in adult microglia - counteracting the age-related decline of protein degradation
A. Stolzing, T. Grune
Combining stem and gene therapy for the aging brain
Clive Svendsen and Soshana Behrstock
Steady-state level of heat shock proteins in tissues of unstressed rats: Effect of age
R. Takahashi, S. Goto
Acute Coronary Syndrome and Co-morbidity in Geriatric Patients
E. Taneva, V. Bogdanova, N. Shtereva
Correlation between lipofuscin accumulation, oxidative stress and mitochondrial damage in cultured rat cardiac myocytes
A. Terman, J.W. Eaton, U.T. Brunk
The Delay and/or Escape of Cardiovascular Disease in Centenarian Offspring
D.F. Terry, M. Wilcox, M.A. McCormick, T.T. Perls
Mechanisms regulating muscle wasting during muscle disuse or aging
J.G. Tidball, H.X. Nguyen, M.J. Spencer
Metabolic substrates of neuronal ageing
E.C. Toescu & J. Xiong
Transcriptional control of telomerase reverse transcriptase in normal endothelial cells. Differences between stimulation by fibroblast growth factor-2 and vascular endothelial growth factor
E. Trivier, D.J. Kurz, Y. Hong, H.L. Huang, J.D. Erusalimsky
Functional analysis of the senescence biomarker Clusterin/Apolipoprotein J in human osteosarcoma cells reveals both a pro- and anti-apoptotic function
I.P. Trougakos, E.S. Gonos
For about 30 years anti-aging treatments have been legally prescribed
S.V. Ukraintseva, K.G. Arbeev, A.I. Michalsky, A.I. Yashin
Cancer as "rejuvenescence"
S.V. Ukraintseva, A.I. Yashin
Pleiotropic activities of TGF-b cytokines on human prostate basal cells: Increased SA-beta-galactosidase activity due to differentiation processes, not as a consequence of premature senescence
G. Untergasser, R. Gander, H. Rumpold, E. Heinrich, E. Plas and P. Berger
Effect of Aging and Caloric Restriction on the 24-hour Release Patterns of DHEAS and Cortisol in Male Rhesus Macaques
H.F. Urbanski, J.L. Downs, V.T. Garyfallou, M.A. Lane, G.S. Roth, D.K. Ingram
Variation in human p53 affects old age survival and cancer mortality
D. van Heemst, on behalf of the Long Life Consortium
Genes affecting stem cells, aging and longevity
Gary Van Zant
Genomic instability in cancer and aging
J. Vijg, R. Bahar, K. Rodriguez, R. Busuttil, M. Dolle, H. van Steeg, J. Campisi, J. Hoeijmakers
Human therapeutic cloning: opportunities and challenges
Michael West
Caloric Restriction Modulates Early Events in Insulin Signaling in Liver and Skeletal Muscle of Rat
Min Zhu, Rafael de Cabo, Mark A. Lane, and Donald K. Ingram.
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