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Abstracts invited or accepted so far
This list includes invited abstracts, those accepted for oral presentation and those accepted for poster presentation.
Free radical view on aging starting under physiological conditions
I.B. Afanas'ev
The role of mtDNA deletion mutations in sarcopenia
J.M. Aiken, D. McKenzie
Respiratory-to-Fermentative (RTF) Shift in ATP Production in Chronic Illness and a Novel Phospholipid Fraction for Clinical Use for Reversing RTF Shift
M. Ali, G. Viole
Sex as a division of labour between mitochondria
J.F. Allen, C.A. Allen
Revolutionizing Transgenesis and Gene Disruptions using P-element Transposition
J.W. Larrick
The Intergenerational Project: Preserving Heritage in a Technological Society
E. Aphek
Protective efficacy of alpha lipoic acid on acetylcholinesterase activity in aged rat brain regions
P. Arivazhagan
Tissue Engineering, Stem Cells and Cloning: Current Concepts and Changing Trends
A. Atala
Poly(ADP-Ribosyl)ation and Telomere Dynamics in Mammalian Cells
S. Beneke, P. Boukamp, A. Bürkle
Synaptic pathology in the brain cortex of old monkeys as an early alteration in senile plaques formation
C. Bertoni-Freddari, P. Fattoretti, T. Casoli, G. Di Stefano, B. Giorgetti, Y. Grossi, M. Balietti, G. Perretta
Cytochemical estimation of cytochrome oxidase activity as a morphofunctional mitochondrial check up
C. Bertoni-Freddari, P. Fattoretti, T. Casoli, G. Di Stefano, B. Giorgetti, Y. Grossi, M. Balietti
Testing mitochondrial metabolic competence by cytochrome oxidase preferential cytochemistry vs. immmunoreactivity of subunit I and IV
P. Fattoretti, C. Bertoni-Freddari, T. Casoli, G. Di Stefano, B. Giorgetti, Y. Grossi, M. Balietti
Level and distribution of microtubule associated protein-2 (MAP2) as an index of dendritic structural dynamics
G. Di Stefano, T. Casoli, P. Fattoretti, M. Balietti, Y. Grossi, B. Giorgetti, C. Bertoni-Freddari
Structural synaptic remodelling in the perirhinal cortex of adult and old rats following object-recognition training
C. Bertoni-Freddari, D. Platano, P. Fattoretti, B. Giorgetti, Y Grossi, M. Balietti, T. Casoli, G. Di Stefano, G. Aicardi
Computer Simulation of Telomere Dynamics and Senescence
K.B. Blagoev, E.H. Goodwin
Telomeres and human disease: a matter of bad ends
M.A. Blasco
Current and Future Stategies for the Treatment of Metabolic Storage Disorders
R.O. Brady
From disease-oriented to aging/longevity-oriented studies
A. Budovsky, K. Muradian, V. Fraifeld
Mitochondrial genome anatomy and species-specific lifespan
G. Lehmann, A. Budovsky, K. Muradian, V. Fraifeld
Poly(ADP-ribosyl)ation capacity of human T lymphocytes in vitro and in vivo as a function of age
K. Annett, A. Bürkle, M. Malaisé, O. Duggan, R. Freeburn, P. Hyland, C. Barnett, A. Wikby, G. Pawelec, Y. Barnett
Memory B-cell subpopulations in aged
G. Colonna-Romano, M. Bulati, A. Aquino, S. Vitello, G. Clesi, C. Caruso
Cellular senescence, cancer and aging
J. Campisi
Association between the HLA-A2 allele and Alzheimer disease
F. Listì, G. Candore, C.R. Balistreri, S. Vasto, M.P. Grimaldi, G. Colonna-Romano, A. Giacalone, V. Orlando, D. Lio, C. Franceschi, C. Caruso
Biology of longevity: role of the immune system
G. Colonna-Romano, G. Candore, A. Aquino, M. Bulati, S. Vitello, D. Lio, I.M. Rea, C. Caruso
Tissue-specific effect of age and caloric restriction diet on mitochondrial DNA content
P. Cassano, A.G. Sciancalepore, A.M.S. Lezza, C. Leeuwenburgh, P. Cantatore, M.N. Gadaleta
Parthenogenetic Embryonic Stem Cells in Primates
J.B. Cibelli
The decay of extra-cellular matrix proteins; an inevitable consequence of old age?
M.J. Collins, S. Ritz-Timme
Understanding and reversing aging of muscle precursor cells
I.M. Conboy
Ex vivo gene delivery of NGF in Alzheimer's Disease
M.H. Tuszynski, J.M. Conner
Membership in high-risk genetic groups predicts Alzheimer's disease and age-at-onset
E.H. Corder, R. Huang, H.M. Cathcart, I.S. Lanham, G.R. Parker, D. Cheng, S.E. Poduslo
The neurosecretory system is hypertrophied in senescence-accelerated mice
D. Crespo, M. Megias, C. Fernandez-Viadero, L. Alonso, R. Verduga
Analysis of HLA-DQA, HLA-DQB frequencies in a group of Sardinian centenarians
A. Crivello, D. Lio, G. Candore, G.I. Forte, L. Scola, G. Colonna-Romano, M.G. Pes, C. Carru, L. Ferrucci, L. Deiana, G. Baggio, C. Franceschi, C. Caruso
Reactivating chaperone-mediated autophagy: the advantages of preserving a selective autophagy
A.M. Cuervo
Tripterine inhibits the expression of adhesion molecules in activated endothelial cells
Deng-hai Zhang, Anthony Marconi, Li-Min Xu, Chun-xin Yang, Guo-wu Sun, Xiao-ling Feng, Shu-min Xu, Chang-quan Ling, Wan-zhang Qin, Georges Uzan, Patrizia d'Alessio
WILT: still crazy after both these years?
A.D.N.J. de Grey
Interspecies SCNT with ES cell mito-rescue: a proposed solution to some key ethical and logistical problems
A.D.N.J. de Grey
SMK-1, an essential regulator of DAF-16/FOXO3a mediated longevity
H. Ma, S. Wolff, D. Burch, G. Maciel, P.J. Woodring, T. Hunter, A. Dillin
Antibody quality in old age
D.K. Dunn-Walters
Cryopreservation of Complex Living Systems: The Missing Link in the Regenerative Medicine Supply Chain
G.M. Fahy
Transfection of CCE Embryonic stem cells with EGFP and BDNF genes by electroporation method
F. Fathi, T. Altiraihi, J. Mowla, M. Movahedin
Glucosepane Crosslink Breakers: Necessity and Prospects
J.D. Furber
Historical dynamics of natural death rate of the population and variations of atmospheric radiocarbon
A.A. Germanskaia
Radiocarbon ageing mechanism
A.M. Germansky, A.A. Germanskaia
Natural death rate variations of the Earth population and radiocarbon ageing mechanism
A.M. Germansky
Telomere Dynamics and Cell Proliferation
E.H. Goodwin, S.M. Bailey, C.K. Sanders, K.B. Blagoev
Alagebrium: Intervention on the A.G.E. pathway modifies deficits caused by aging and diabetes
H.B. Haimes
Can continuous regeneration lead to immortality? Studies in the MRL mouse
E. Heber-Katz
Caloric restriction protects mitochondrial function with aging in skeletal and cardiac muscles
R.T. Hepple, D.J. Baker, M. McConkey, T. Murynka, R. Norris
Negligible senescence - how will we know it when we see it?
C.B. Heward
Revitalization and life span extension by xenogenic fetal materials: laboratory rodent and cell culture studies
G. Hofecker, A. Strasser, H. Niedermüller, C. Gabler
Global loss of imprinting in embryonic stem cells leads to widespread tumorigenesis in adult mice
T.M. Holm, L. Jackson-Grusby, T. Bambrick, Y. Yamada, W.M. Rideout 3rd, R. Jaenisch
Cryptobiosis, ageing and cancer: yin-yang balancing of signalling networks
Z. Huang, A. Tunnacliffe
Patient-specific embryonic stem cells derived from human SCNT-blastocysts
Woo Suk Hwang
Alzheimer's, Huntington's and Prion Diseases - why are misfolded proteins so interesting, but so destructive?
V.M. Ingram, B.J. Blanchard, A. Ahmad, L. Zhang, L. Rozeboom
Herpes simplex virus type 1 in brain and apolipoprotein E type 4 allele: a dangerous liaison for Alzheimer's disease
R.F. Itzhaki, S. J. Shipley, C.B. Dobson, M.A. Wozniak
Oxygen free radicals production and DNA damage/repair activity in lymphocytes of elderly subjects
J. Jajte, J. Grzegorczyk, J. Błasiak, A. Sapota
Abnormal lysosomal processing of internalized cholesteryl esters in macrophages
W.G. Jerome
Oxidized lipids in atherosclerotic macrophages: what role do they play in foam cell formation?
W. Jessup
Extracellular redox state: refining the definition of oxidative stress in aging
D.P. Jones
Role of insulin action and gene expression in adipose tissue in aging
C.R. Kahn, M. Katic, M. Bluher
Manipulating the intracellular fate of an aggregate-prone protein
S. Kaushal
Senescence as morbus reponibilis
A.V. Khalyavkin, A.I. Yashin
Statistical issues of regression analysis on development of an age-predictive equation
K. Kikkawa
For a tree time can be slowed down: Analysis of proliferation capacity of tree cells
B.E. Flanary, G. Kletetschka
Soft strategies for postponing ageing and prolonging human life
Ü. Kristjuhan
Chaperones of longevity
J. Krøll
A-beta Immunotherapy: Lessons From Mice, Monkeys and Men
C.A. Lemere, M. Maier, T.J. Seabrook
Nucleic acid delivery to mammalian mitochondria - myth or reality?
M. Koulintchenko, A. Dietrich, R.N. Lightowlers
Analysis of candidate genes in celiac disease. A tool to identify life threatening associated genes?
D. Nuzzo, F. Cataldo, L. Scola, G.I. Forte, A. Crivello, A. Giacalone, S. Accomando, G. Candore, C. Caruso, D. Lio
Psycho-social aspects and zinc status: is there a relationship in favour of a successful ageing?
F. Marcellini, C. Giuli, R. Papa, E. Mocchegiani
A novel form of ALT telomere maintenance in human cells
David Cavazos, Richard Montellano, Qijun Chen, F. Brad Johnson, and Robert A. Marciniak
Protection and selection for gene therapy in the haemopoietic system
G. Margison, L.J. Fairbairn
The aging gut motility decay: may symbiotics be acting as biological pace-makers?
Y. Metugriachuk, F. Marotta, O. Kuroi, K. Pavasuthipaisit, J. Tsuchiya, A. Lorenzetti, E. Fesce, E. Minelli
Liver exposure to xenobiotics: the aging factor and potentials for novel nutraceuticals
F. Marotta, P. LeCroix, M. Harada, K. Masulair, P. Safran, A. Lorenzetti, S.K. Ono-Nita, P. Marandola
Age-Related Susceptibility Of Red Blood Cells To Oxidative Stress: A Preliminary Nutraceutical Approach
F. Marotta, P. Marandola, C. Yoshida, L. Packer
Increase of vaccines adjuvanticity by succinylation of vaccine antigen
A.V. Martynov, E.M. Babych, M.V. Smelyanskaya
Genetic modification of hematopoietic stem cells: from bench to bedside....and back
F. Mavilio
Age-dependent Mitochondrial Abnormalities and Structural Changes in Rat Kidney Are Delayed by Adult-onset Calorie Restriction
S.H. McKiernan, V.C. Tuen, J.M. Aiken
Gene therapy that safely targets and kills tumor cells throughout the body
D. Meruelo, J. Tseng, A. Hurtado, B. Levin, C. Pampeno
How Evolutionary Thinking Affects our Ideas about Aging Interventions
J. Mitteldorf
Zinc homeostasis in aging: two elusive faces of the same metal
E. Mocchegiani, L. Costarelli, R. Giacconi, C. Cipriano, E. Muti, M. Malavolta
Enzymic Repair and Prevention of Chemical Aging by the Maillard reaction in Vivo
V.M. Monnier, D.R. Sell, Xinle Wu, Dai Zhenyu
Catechin-vanilloid synergies with potential clinical applications in cancer
D.M. Morré, D.J. Morré
Aging-related cell surface ECTO-NOX protein, arNOX, a preventive target to reduce atherogenic risk in the elderly
D.J. Morré, D.M. Morré
Refining oxidative aging theories with antioxidant enzyme knockout mice
F. Muller
Autophagy in Alzheimer's Disease Pathogenesis
R.A. Nixon
Selective Accumulation of mtDNA Deletion Mutations in Aged Skeletal Muscle
J.W. Pak, J.M. Aiken
Delivery of enzymes and neurotrophic proteins to treat CNS disorders
W. Pan, A.J. Kastin
Natural substances that regenerate and heal - my 20 years experience
J.G. Paraki
Mitochondrial superoxide generation causes heterogeneity in replicative senescence
J.F. Passos, K. Schäuble, G. Saretzki, T. von Zglinicki
Does stem cell therapy for ischemic cardiomyopathy result in the improvement of congestive heart failure?
A.N. Patel
Immunorejuvenation in the elderly
G. Pawelec, S. Koch, C. Gouttefangeas, A. Wikby
Ageing, amyloid and amyloidosis: from pathogenesis to therapy
M.B. Pepys
Encouraging support for the funding of aging research through the use of competitive prizes
K. Perrott, D. Gobel, A.D.N.J. de Grey
Scientific Controversy as Farce: Disciplining Homeopathic Claims
C.J. Picart
Using zinc finger nucleases to manipulate the mammalian genome
M.H. Porteus
The Supercentenarian Research Foundation
S.R. Primmer, E. Bergman, D. Platika, L.S. Coles, A.D.N.J. de Grey, K. Ullis, D. Gobel, R.D. Young
To Engineer a Heart
B.D. Ratner
Immune sensing of latent cytomegalovirus reactivation and its possible impact on immune senescence
M.J. Reddehase
Chromatin remodeling may enforce cell senescence
K. Riabowol
The Microbiological Foundation for Bioremediating Intracellular Aggregates
B.E. Rittmann
Macroautophagy upregulation - a candidate therapeutic strategy to enhance clearance of toxic intracellular aggregate-prone proteins
D.C. Rubinsztein
Enhanced reprogramming to facilitate production of somatic cell NT ES cell lines
A. Rybouchkin, Y. Kato, Y. Tsunoda
Telomere dynamics and telomerase-inhibitor cancer therapy
C.K. Sanders, K.B. Blagoev and E.H. Goodwin
Telomerase decreases ROS levels but does not counteract telomere shortening under oxidative stress
S.S. Ahmed, J. Passos, T. von Zglinicki, G.C. Saretzki
Aging research enabled by patient-specific embryonic stem cells derived from human SCNT-blastocysts
Woo Suk Hwang, Sung Il Roh, Byeong Chun Lee, Sung Keun Kang, Dae Kee Kwon, Sue Kim, Sun Jong Kim, Sun Woo Park, Hee Sun Kwon, Chang Kyu Lee, Jung Bok Lee, Jin Mee Kim, Curie Ahn, Sun Ha Paek, Sang Sik Chang, Jung Jin Koo, Hyun Soo Yoon, Jung Hye Hwang, Youn Young Hwang, Ye Soo Park, Sun Kyung Oh, Hee Sun Kim, Jong Hyuk Park, Shin Yong Moon, Gerald Schatten
Sustained Stromal Stem Cell Self-Renewal and Osteoblastic Differentiation During Aging
P.C. Schiller, G. D'Ippolito, G.A. Howard, B.A. Roos
Immunomodulatory vaccines against autoimmune diseases
M. Sela
Mice with improved systems for cellular quality control: super-p53 and super-p16/ARF mice
M. Serrano, I. Garcia-Cao, M. Garcia-Cao, A. Matheu, M.A. Blasco
Tissue Engineering Teeth
P.T. Sharpe
Ageing and oral health related to quality of life
N. Shtereva
Microheteroplasmy and protofection - the why and how of mtDNA replacement therapy
R. Smigrodzki
Clinical Application of Umbilical Cord Blood Mesenchymal Stem Cells
Chang Hun Song
The Lipofuscin of the Retinal Pigment Epithelium
J.R. Sparrow
To Make an New Intestinal Mucosa
M. Stelzner
Senescence in mesenchymal stem cells: the effects of reduced culture temperature and media glucose concentration
A. Stolzing, A. Scutt
Apoptosis, genome maintenance, and aging
Y. Suh
The Impact of Aging on CD4 T Cell Function
S. Swain
Immune Tolerance Induction: From Bench to Bedside
M. Sykes
Is thrombolytic therapy effective in elderly patients?
E. Taneva
Thymic Rejuvenation by Engineered Cells Secreting IL-7 in situ
J.A. Phillips, E.L. Virts, M.L. Thoman
Leptin and Longevity: Blocking the consequences of lipid overload
R.H. Unger
Cellular ageing in fibroblast cultures from elderly aged 90 years old
A.B. Maier, R.G.J. Westendorp, D. van Heemst
nACHR4 594C/T SNP in Alzheimer Disease
S. Vasto, D. Nuzzo, F. Listì, C.R. Balistreri, D. Di Carlo, V. Ditta, M.P. Grimaldi, D. Lio, C. Franceschi, G. Candore, C. Caruso
Genome Structure May Control Lifespan
B. Villeponteau
Deciphering Free-Radical Code of Aging
S. Volovik
Factors that might affect the allotopic replacement of a damaged mitochondrial DNA-encoded protein
S.J. Zullo J.M. Eisenstadt, C.R. Merril, H. Weiner
Strategies for the Reversal of the Aging of Human Somatic Cells
M.D. West, I. Klimanskaya, R.P. Lanza
Tackling the diseases of old age; progress towards an Alzheimer's therapeutic
S.M. Wilson, J. Patel, S. Dealler, R. Rosedale, C.J. Stanley
Can a single subunit NADH dehydrogenase rescue complex I defects?
T. Yagi, B.B. Seo, E. Nakamaru-Ogiso, T.R. Flotte, A. Matsuno-Yagi
Nanog changing in mouse kidneys with age
Quan-jian Yan, Xiang-mei Chen, Yu-mei Zhang, Yuansheng Xie, Suo-zhu Shi, Bo Fu, Quan Hong, Guo-shuang Xu, Xue-guang Zhang, Han-yu Zhu, Di Wu, Yang Lv, Yun-Hui Zhang
Nuclear insulin-like growth factor binding protein-3 induces apoptosis and is targeted to ubiquitin/proteasome-dependent proteolysis
W. Zwerschke
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