The Drug Pricing System That Could Use Disrupting

The Drug Pricing System That Could Use Disrupting

We all want a healthcare system that is more productive and efficient in finding innovative solutions to illnesses and diseases of aging. That is why it is important to look at the factors that need disruption in our journey to creating an inclusive and sustainable healthcare system.

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The Methuselah Foundation Successfully Closes its Boutique Venture Fund

The Methuselah Foundation Successfully Closes its Boutique Venture Fund

The Methuselah Fund or M Fund is mission-oriented and was conceived after successful angel investments by the Methuselah Foundation. The M Fund's investment thesis is based on six strategies aimed at increasing healthy longevity and its current portfolio includes four exciting companies.

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Society for Gero-Engineering and Technology (SGET)

Society for Gero-Engineering and Technology (SGET)

For a while, we have seen that anti-aging is rapidly becoming an engineering challenge rather than a mere fantasy. To this point, our Foundation is also working on helping create a professional society focused on Geroengineering. Enter, the Society of Gero-Engineering and Technology, or SGET.

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Biological Age Estimation Methods: A Systematic Review

Biological Age Estimation Methods: A Systematic Review

Aging is a complicated process and is highly varied among individuals. We all have that friend who "doesn't look a day over 30" well into middle-age, and the less fortunate friend who isn't aging "gracefully". You may notice aging variability within your own body. Perhaps you have overall excellent health, but your digestion has slowed or you have sleep-pattern changes. Research shows that the quantity of years is a poor estimator as an index of the aging process. Even twins often have different biological or functional ages, and within an individual, organs may age at different rates. 

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The Gut Bacteria Is More Important Than You Think!

The Gut Bacteria Is More Important Than You Think!

For centuries, man has been attempting to extend the healthy human lifespan by investigating the correlation between health and the microbiome. In the past, these methods have been largely unsuccessful. New research is emerging that focuses on the 29 strains of E. coli that protect against age-associated diseases, causing the host to live at least 10% longer and healthier.

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Another Threat to Our Longevity: Chronic Dosing and Overprescribing

Another Threat to Our Longevity: Chronic Dosing and Overprescribing

What happens when the industry created to keep you alive pushes products that ultimately aid in your death? We are often concerned about incentives in the healthcare industry to prescribe medicine when it is not necessary and even when a simple lifestyle change would achieve the same beneficial effects.

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The Investment Scene for Longevity is Heating Up!

The Investment Scene for Longevity is Heating Up!

Over 10 years ago, we realized that investing in longevity companies has a two-fold benefit. Such investments accelerate products into the market that we all benefit from and also pours more capital into private research, resulting in breakthroughs in the longevity space. 

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Want To Reduce Your Senescent Cells? An Argument For Diet-Induced Weight Loss

Want To Reduce Your Senescent Cells? An Argument For Diet-Induced Weight Loss

Cellular senescence is an increasingly popular topic. Dysfunctional cells have been implicated in numerous age-related dysfunctions. While the efforts to remove these senile cells have been growing, this study shows that at least one form of cellular senescence can be addressed without drugs or other high-tech interventions.

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Understanding Cell Reprogramming: The Promising Cautious Approach

Understanding Cell Reprogramming: The Promising Cautious Approach

The four "Yamanaka factors" have been known to induce pluripotency for some time. Forced expression of these four genes has been reported to turn an adult cell into what appears to be a pluripotent stem cell, with all that entails. However, this report illustrates that stem cell differentiation is a continuum.

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N of One: An Experiment In Not Flying Breathlessly

N of One: An Experiment In Not Flying Breathlessly

On a recent trip to California, my goal was to document an aircraft’s actual interior cabin altitude, versus the altitude of that aircraft’s distance above the ground. Finding this altitude would tell me how much oxygen would be in the cabin, where lower altitudes would mean more available oxygen.

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