Scientists Correct Mutated Gene that Causes Sickle Cell Disease in Stem Cells

Scientists Correct Mutated Gene that Causes Sickle Cell Disease in Stem Cells

For the first time, scientists were able to correct the genetic mutation that causes sickle cell disease in stem cells.

In a collaborative effort, researchers at UC Berkeley, UC San Francisco Benioff Children’s Hospital Oakland Research Institute (CHORI), and the University of Utah School of Medicine fixed the mutation in modified stem cells from patients with the condition using a CRISPR/Cas9 gene editing approach.

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Making memories stronger and more precise during aging

Making memories stronger and more precise during aging

When it comes to the billions of neurons in your brain, what you see at birth is what get — except in the hippocampus. Buried deep underneath the folds of the cerebral cortex, neural stem cells in thehippocampus continue to generate new neurons, inciting a struggle between new and old as the new attempts to gain a foothold in the memory-forming center of the brain.

In a study published online today in Neuron, Harvard Stem Cell Institute (HSCI) researchers atMassachusetts General Hospital and the Broad Institute of MIT and Harvard in collaboration with an international team of scientists found they could bias the competition in favor of the newly generated neurons.

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BREAKING: Methuselah Partnering with NASA

BREAKING: Methuselah Partnering with NASA

NASA, in partnership with the nonprofit Methuselah Foundation’s New Organ Alliance, is seeking ways to advance the field of bioengineering through a new prize competition.

The Vascular Tissue Challenge offers a $500,000 prize to be divided among the first three teams that successfully create thick, metabolically-functional human vascularized organ tissue in a controlled laboratory environment.

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