Breaking the Vascularity Barrier

Breaking the Vascularity Barrier

There are 3D bioprinters but no 3D printed usable organs. Why is that? Microvascularization is a key rate limiter preventing humans needing an organ transplant from having it made available to them. In other words, blood needs to get to the 3D printed tissue in order for the tissue to remain alive. Thankfully, a start-up we have proudly supported from inception is developing the necessary tools to solve the microvascularization challenge so that we can have functioning 3D printed organs.

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Cell Reprogramming Leads to Reversal in Cell Aging!

Cell Reprogramming Leads to Reversal in Cell Aging!

An impressive team at Stanford lead by Vittorio Sebastiano, Jay Sarkar, and Marco Quarta has found a way to turn adult cells into younger cells. That way, the cells don’t forget their assigned tasks since they maintain their cell type, but have the added advantage of having restored youthful performance.

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Are There Longevity Vitamins, Like There Are Survival Vitamins?

Are There Longevity Vitamins, Like There Are Survival Vitamins?

What we know as “essential vitamins and minerals” are compounds whose absence has been observed to be immensely detrimental or even fatal to humans. Think of death by scurvy (vitamin C deficiency) or pellagra (niacin deficiency). But an important question to ask for each essential vitamin and mineral is: “over what timeframe do detrimental effects of deficiency manifest themselves?”

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Family & Longevity: Genetics Can Dictate How Long You May Live

Family & Longevity: Genetics Can Dictate How Long You May Live

Here is an interesting fact for the dinner table… many studies have correlated longevity with genes and you may find out just how likely you are to surpass the 100 year mark. Did you know that individuals who have centenarian parents have been found to be less likely to have the age-related diseases that are common among older adults?

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The Drug Pricing System That Could Use Disrupting

The Drug Pricing System That Could Use Disrupting

We all want a healthcare system that is more productive and efficient in finding innovative solutions to illnesses and diseases of aging. That is why it is important to look at the factors that need disruption in our journey to creating an inclusive and sustainable healthcare system.

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The Gut Bacteria Is More Important Than You Think!

The Gut Bacteria Is More Important Than You Think!

For centuries, man has been attempting to extend the healthy human lifespan by investigating the correlation between health and the microbiome. In the past, these methods have been largely unsuccessful. New research is emerging that focuses on the 29 strains of E. coli that protect against age-associated diseases, causing the host to live at least 10% longer and healthier.

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Another Threat to Our Longevity: Chronic Dosing and Overprescribing

Another Threat to Our Longevity: Chronic Dosing and Overprescribing

What happens when the industry created to keep you alive pushes products that ultimately aid in your death? We are often concerned about incentives in the healthcare industry to prescribe medicine when it is not necessary and even when a simple lifestyle change would achieve the same beneficial effects.

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The Investment Scene for Longevity is Heating Up!

The Investment Scene for Longevity is Heating Up!

Over 10 years ago, we realized that investing in longevity companies has a two-fold benefit. Such investments accelerate products into the market that we all benefit from and also pours more capital into private research, resulting in breakthroughs in the longevity space. 

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Want To Reduce Your Senescent Cells? An Argument For Diet-Induced Weight Loss

Want To Reduce Your Senescent Cells? An Argument For Diet-Induced Weight Loss

Cellular senescence is an increasingly popular topic. Dysfunctional cells have been implicated in numerous age-related dysfunctions. While the efforts to remove these senile cells have been growing, this study shows that at least one form of cellular senescence can be addressed without drugs or other high-tech interventions.

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Understanding Cell Reprogramming: The Promising Cautious Approach

Understanding Cell Reprogramming: The Promising Cautious Approach

The four "Yamanaka factors" have been known to induce pluripotency for some time. Forced expression of these four genes has been reported to turn an adult cell into what appears to be a pluripotent stem cell, with all that entails. However, this report illustrates that stem cell differentiation is a continuum.

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Decades and Billions of Dollars Have Been Lost in the War Against Alzheimer's Disease

Decades and Billions of Dollars Have Been Lost in the War Against Alzheimer's Disease

At Methuselah Foundation we understand that the war against AD is one that humanity cannot afford to loose. We applaud revisiting the roadmap that will lead us to a cure. Writer John Carroll analyses this imperative in the Endpoints News article titled "After yet another PhIII Alzheimer’s failure, experts try to map a path out of the wrecking field."

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