A remarkable report was published on July 11, 2018 which some readers may have heard about. There are not many interventions known to improve physical function and extend remaining lifespan when given to mice in old age. However, the consistently positive results reported in this study suggest that, at the very least, using this particular senolytic cocktail intermittently appears to have multiple benefits in old mice, and suggest that senolytics may be worth testing in aging humans.