Progress on a better alternative to animal testing

Progress on a better alternative to animal testing

Medicine depends on animal testing to assess drug safety and efficacy. The problem is that animal tests often fail to predict clinical responses. This means drugs that look promising in animal studies often fail to deliver in human clinical trials. In fact, one study found that more than 86% of drugs found to be safe and effective in animal studies fail to get FDA approval. A new article in Nature Biomedical Engineering reports on the creation of what may eventually lead to a replacement for animal testing.

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Could This "Human Body on a Chip" Replace Rodent Models?

Could This "Human Body on a Chip" Replace Rodent Models?

Some 60%-90% of drugs that are successful in rodents… fail in humans. However, researchers at Harvard University and Tel Aviv University have developed a new model that might address this problem: mini human organs on a chip. These separate “organ chips” can be connected to create a “mini human on a chip”, to test the effects of different treatments and medications on multiple organs and systems.

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EPA to Eliminate All Mammal Testing by 2035

EPA to Eliminate All Mammal Testing by 2035

It can be said that cancer has been cured dozens of times over in mice. Oftentimes though, the results obtained in the lab aren’t translatable to humans with the same conditions. This uncertainty often leads to misleading results, frustration, and a waste of resources. With this in mind, the EPA has recently announced that they will stop conducting or funding studies on mammals by 2035. Read More >

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