The latest on Methuselah, health span research, and regenerative medicine
Intestinal worms have long caused suffering in humans, but has our bias against a handful of harmful helminths led us to slaughter billions of helpful ones? Is our quest as humans to eradicate parasitic worms being accomplished to our detriment? And if we could treat or even prevent many of our modern inflammatory diseases with harmless intestinal worms, why don’t we?
Read MoreLight exposure on the retina of the eye plays a critical role in entraining the circadian rhythm—the daily oscillation of tissue function, including the secretion of different hormones at different times.
Read MoreThere are 3D bioprinters but no 3D printed usable organs. Why is that? Microvascularization is a key rate limiter preventing humans needing an organ transplant from having it made available to them. In other words, blood needs to get to the 3D printed tissue in order for the tissue to remain alive. Thankfully, a start-up we have proudly supported from inception is developing the necessary tools to solve the microvascularization challenge so that we can have functioning 3D printed organs.
Read MoreAn impressive team at Stanford lead by Vittorio Sebastiano, Jay Sarkar, and Marco Quarta has found a way to turn adult cells into younger cells. That way, the cells don’t forget their assigned tasks since they maintain their cell type, but have the added advantage of having restored youthful performance.
Read MoreOn a recent trip to California, my goal was to document an aircraft’s actual interior cabin altitude, versus the altitude of that aircraft’s distance above the ground. Finding this altitude would tell me how much oxygen would be in the cabin, where lower altitudes would mean more available oxygen.
Read MoreWe modestly present a journey into our personal experience with "near field environmental factors" and health. This series will be the first entry in what we hope will become a shared resource that helps us all get better and better. Welcome to N of One!
Read MoreThe elderly have wisdom of great value to all, but few listen. Their story is worth being heard. If things don’t change, we will all share their experience. This first-person narrative is the result of years of interviews and the extensive experience of a Registered Nurse specializing in Geriatrics. We invite you to live a day in the live of a 90 year old.
Read MoreWhat we know as “essential vitamins and minerals” are compounds whose absence has been observed to be immensely detrimental or even fatal to humans. Think of death by scurvy (vitamin C deficiency) or pellagra (niacin deficiency). But an important question to ask for each essential vitamin and mineral is: “over what timeframe do detrimental effects of deficiency manifest themselves?”
Read MoreWhat defines an average 90-year-old scientifically?
What defines a 50-year-old?
How could we make 90 the new 50 by 2030?
The epigenetic remodeling accomplished by this protocol appears promising, and may help us to rejuvenate older humans.
Read MoreHere is an interesting fact for the dinner table… many studies have correlated longevity with genes and you may find out just how likely you are to surpass the 100 year mark. Did you know that individuals who have centenarian parents have been found to be less likely to have the age-related diseases that are common among older adults?
Read MoreWe all want a healthcare system that is more productive and efficient in finding innovative solutions to illnesses and diseases of aging. That is why it is important to look at the factors that need disruption in our journey to creating an inclusive and sustainable healthcare system.
Read MoreThe quest for healthier and longer lives should be inclusive and understood by all around the Earth. We are happy to see Forbes Africa publish an article focused on the impact of the longevity industry in this vast and beautiful continent.
Read MoreThe Methuselah Fund or M Fund is mission-oriented and was conceived after successful angel investments by the Methuselah Foundation. The M Fund's investment thesis is based on six strategies aimed at increasing healthy longevity and its current portfolio includes four exciting companies.
Read MoreOne area of research for improving health and reducing the comorbidities of aging is brown adipose tissue. Brown adipose tissue improves energy metabolism and has protective mechanisms against obesity.
Read MoreFor a while, we have seen that anti-aging is rapidly becoming an engineering challenge rather than a mere fantasy. To this point, our Foundation is also working on helping create a professional society focused on Geroengineering. Enter, the Society of Gero-Engineering and Technology, or SGET.
Read MoreAging is a complicated process and is highly varied among individuals. We all have that friend who "doesn't look a day over 30" well into middle-age, and the less fortunate friend who isn't aging "gracefully". You may notice aging variability within your own body. Perhaps you have overall excellent health, but your digestion has slowed or you have sleep-pattern changes. Research shows that the quantity of years is a poor estimator as an index of the aging process. Even twins often have different biological or functional ages, and within an individual, organs may age at different rates.
Read MoreOur friends at LEAF took the time to ask some interesting questions to our CEO and longevity community pioneer, David Gobel. We hope you enjoy his answers to these great questions.
Read MoreWe are excited to start seeing one of our initiatives getting more press coverage. Oisin Biotechnologies and its approach to senolytics is something we are proud of. We invite you to learn more at oisinbio.com!
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